Molecular Formula | C11H15ClN4O4 |
Molar Mass | 302.72 |
Melting Point | 268-270°C |
Solubility | Soluble in DMSO |
Appearance | Solid |
Color | Off-White to Pale Beige |
Storage Condition | Hygroscopic, Refrigerator, under inert atmosphere |
Stability | Hygroscopic |
Use | Forodesine hydrochloride is a transition-state analog inhibitor of purine nucleoside phosphorylase. |
Reference Show more | 1: Argnani L, Broccoli A, Zinzani PL. Cutaneous T-cell lymphomas: Focusing on novel agents in relapsed and refractory disease. Cancer Treat Rev. 2017 Dec;61:61-69. doi: 10.1016/j.ctrv.2017.10.007. Epub 2017 Oct 28. Review. PubMed PMID: 29102679. 2: Lewis DJ, Duvic M. Forodesine in the treatment of cutaneous T-cell lymphoma. Expert Opin Investig Drugs. 2017 Jun;26(6):771-775. doi: 10.1080/13543784.2017.1324569. Epub 2017 May 5. Review. PubMed PMID: 28447489. 3: Thomas X, Le Jeune C. Treating adults with acute lymphocytic leukemia: new pharmacotherapy options. Expert Opin Pharmacother. 2016 Dec;17(17):2319-2330. Epub 2016 Oct 31. Review. PubMed PMID: 27759440. 4: Freitas EO, Nico D, Alves-Silva MV, Morrot A, Clinch K, Evans GB, Tyler PC, Schramm VL, Palatnik-de-Sousa CB. Immucillins ImmA and ImmH Are Effective and Non-toxic in the Treatment of Experimental Visceral Leishmaniasis. PLoS Negl Trop Dis. 2015 Dec 23;9(12):e0004297. doi: 10.1371/journal.pntd.0004297. eCollection 2015 Dec. PubMed PMID: 26701750; PubMed Central PMCID: PMC4689457. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.303 ml | 16.517 ml | 33.034 ml |
5 mM | 0.661 ml | 3.303 ml | 6.607 ml |
10 mM | 0.33 ml | 1.652 ml | 3.303 ml |
5 mM | 0.066 ml | 0.33 ml | 0.661 ml |